]> Good L, Panas RM Volume 1 Issue 1 In Process 10.31531/edwiser.jcegh.1000101 For many patients with inflammatory bowel disease the need for a proctocolectomy with the establishment of a Jpouch is a necessary procedure In some patients an inflammatory condition of the Jpouch known as pouchitis contributes to symptoms that include bloody diarrhea urgency dehydration and endoscopic evidence of inflammation The specific cause of pouchitis is unknown and there is also no universally accepted or FDAapproved treatment for pouchitis As such many patients are managed empirically with multiple medication regimens Ten patients with pouchitis who experienced flares and poor management of their condition with conventional drug treatments had severe unremitting chronic diarrhea It was not until the addition of serumderived bovine immunoglobulinprotein isolate SBI that 8 of 10 patients experienced satisfactory management of their pouchitisassociated diarrhea An ongoing analysis of 7 of these 10 patients for up to 5 years found that 5 of these patients experienced ongoing management of their diarrhea associated with pouchitis with no reports of any flares with the remaining 2 patients reporting a few minor flares One patient out of the 5 analyzed was able to discontinue all adjunctive therapies Three of the 10 original patients were losttofollow up or moved out of state and no further details were available for ongoing analysis As a medical food SBI is not intended for the specific treatment of pouchitis but these patients demonstrate beneficial effects in the longterm management of diarrheaassociated with pouchitis All Published Work is Licensed under a creative commons attribution 4.0 international license 2024